Microenvironmental/LCA Modeling
Microenvironmental and life cycle analysis (LCA) modeling
Computational Analysis Tools
| Resource | Developer |
|---|---|
| AMEM – ADL Migration Estimation Model | USEPA |
| BenMAP (“estimate the health impacts and economic benefits […] when populations experience changes in air quality”) | USEPA |
| CalTOX | California DTSC |
| ConsExpo (a set of models “that enables the estimation and assessment of exposure to substances from consumer products that are used indoor and their uptake by humans”) | RIVM |
| CONTAM | NIST |
| COS.SIM (“Agent Based Traffic MicroSimulation”) | COS.SIM development team |
| Creme – RIFM Aggregate Exposure Model for Fragrance Materials | Creme Global and RIFM |
| DEEM-FCID/ Calendex – Dietary Exposure Evaluation Model-Food Commodity Intake Database/ Calendex | USEPA |
| DMR Pollutant Loading Tool – Discharge Monitoring Report Pollutant Loading Tool | USEPA |
| EMI – Exposure Model for Individuals | USEPA |
| EPANET (“Models the Hydraulic and Water Quality Behavior of Water Distribution Piping Systems”) | USEPA |
| European AirBase reporting stations | European Environment Agency |
| EUSES – European Union System for the Evaluation of Substances | European Commission, JRC, IHCP |
| FACET – Flavourings, Additives and food Contact materials Exposure Task | Creme Global and collaborators |
| GLEAMviz – Global Epidemic and Mobility model | Northeastern University, ISI Foundation and Indiana University |
| iSTREEM | American Cleaning Institute |
| i-SVOC (“application for dynamic modeling of the emissions, transport, sorption, and distribution of semi-volatile organic compounds (SVOCs) in the indoor environment”) | USEPA |
| MCCEM – Multi-Chamber Concentration and Exposure Model | Versar Inc. and USEPA |
| OpenFOAM | OpenCFD Ltd, ESI Group |
| P2P – Pollution Prevention Progress (see TRACI) | USEPA |
| Phoenics | CHAM |
| PIRAT – Pesticide Inert Risk Assessment Tool | USEPA |
| PRoTEGE – Prioritization/Ranking of Toxic Exposures with GIS Extension | Computational Chemodynamics Laboratory |
| Raidar | CEMC, Canada |
| SWIMODEL – Swimmer Exposure Assessment Model | USEPA |
| SystemsReality | USEPA |
| TRACI – Tool for the Reduction and Assessment of Chemical and other Environmental Impacts (previously, P2P) | USEPA |
| USEtox – UNEP-SETAC (Life Cycle Initiative) Tox | USEtox development team |
| VegScape – Vegetation Condition Explorer | USDA National Agricultural Statistics Service |
Information Portals and Databases
| Resource | Developer |
|---|---|
| AHS – American Housing Survey | US Census Bureau |
| Allergome | Allergome platform development team |
| American Cleaning Institute Cleaning Product Ingredient Inventory | American Cleaning Institute |
| ATUS – American Time Use Survey | U.S. Bureau of Labor Statistics |
| BRFSS – Behavioral Risk Factor Surveillance System | CDC |
| California Safe Cosmetics Program Product Database | California Safe Cosmetics Program, California Department of Public Health |
| caNanoLab – cancer Nanotechnology Laboratory | NCI (National Cancer Institute), NIH |
| CBECS – Commercial Buildings Energy Consumption Survey | U.S. Energy Information Administration |
| CDC WONDER – Wide-ranging Online Data for Epidemiologic Research | CDC |
| Census of Agriculture | USDA NASS |
| CHAD – Consolidated Human Activity Database | USEPA |
| ChemView | USEPA |
| Child-Specific Exposure Factors Handbook | USEPA |
| Consumer Expenditure Survey | U.S. Bureau of Labor Statistics |
| Consumer Products Inventory (“inventory of nanotechnology-based consumer products introduced on the market”) | The Project on Emerging Nanotechnologies |
| CPCat – Chemical and Product Categories | USEPA |
| CPID – Consumer Product Information Database | CDC and DeLima Associates, Virginia, USA |
| CSFII – Continuing Survey of Food Intakes by Individuals | USDA |
| DSID – Dietary Supplement Ingredient Database | USDA Nutrient Data Laboratory and Office of Dietary Supplements, NIH |
| DWS – Drinking Water Standards | USEPA |
| EAFUS – Everything Added to Food in the United States | USFDA |
| ECETOC Science Areas – European Centre for Ecotoxicology and Toxicology of Chemicals Science Areas | ECETOC |
| EPA-Expo-Box – EPA’s EXPOsure toolBOX (“A Toolbox for Exposure Assessors”) | USEPA |
| Esri Business Analyst | Esri |
| ExpoCastDB – Exposure Forecaster Database | USEPA |
| FACET – Flavourings, Additives and food Contact materials Exposure Task | Creme Global and collaborators |
| Factual (“Global Products with Ingredients and Nutrition”) | Factual Inc. |
| GNPD – Mintel Global New Products Database | Mintel Group Ltd. |
| GoodGuide (“source of information on health, environmental, and social impacts of consumer products”) | GoodGuide team |
| HEDS – Human Exposure Database System | USEPA |
| HPD – Household Products Database | National Library of Medicine |
| HPVIS – High Production Volume Information System | USEPA |
| iemHUB (“online community resource for those involved in the development, evaluation, and application of environmental models”) | iemHUB team |
| Information Collection Rule Drinking Water Microbial And Disinfection Byproduct Information | USEPA |
| InterNano | National Nanomanufacturing Network |
| Nanomaterial Registry | RTI International |
| Nanowerk Nanotechnology Products and Applications | Nanowerk |
| National Nutrient Database for Standard Reference | USDA |
| NCOD – National Contaminant Occurrence Database | USEPA |
| NHANES – National Health and Nutrition Examination Survey | CDC |
| NHEXAS – National Human Exposure Assessment Survey (project completed) | USEPA |
| NOES – National Occupational Exposure Survey | CDC – NIOSH |
| NPDWR – National Primary Drinking Water Regulations | USEPA |
| NWIS – National Water Information System | US Geological Survey |
| PDP – Pesticide Data Program | USDA ARS |
| RIOPA – Relationships of Indoor, Outdoor, and Personal Air | EOHSI and Health Effects Institute |
| SDWIS – Safe Drinking Water Information System | USEPA |
| Skin Deep Database | Environmental Working Group |
| SocDynamics.org (Modeling Social Dynamics) | SocDynamics.org development team |
| SPARTAN – Surface PARTiculate mAtter Network | SPARTAN Network team |
| TDS – Total Diet Study | USFDA |
| TEAM – Total Exposure Assessment Methodology Study | USEPA |
| The Nanodatabase | The Ecological Council, DTU Environment and Danish Consumer Council, Denmark |
| United Nations Statistical Yearbook | United Nations |
| US Census Survey | US Census Bureau |
| WATERS – Watershed Assessment, Tracking & Environmental Results System | USEPA |
| WWEIA – What We Eat In America, NHANES | USDA ARS and CDC |
Socioeconomic/LSB Modeling
Socioeconomic and Life Stage Behavior (LSB) modeling
Computational Analysis Tools
| Resource | Developer |
|---|---|
| Agent Analyst (“Agent Based Modeling Extension for ArcGIS”) | University of Redlands, Argonne National Laboratory |
| AMP – Agent Modeling Platform | Eclipse Foundation |
| ANTHROPAC (“program for cultural domain analysis”) | Analytic Technologies |
| AnyLogic (“simulation tool that supports Discrete Event, Agent Based, and System Dynamics Simulation”) | AnyLogic Company |
| Ascape (“developing and exploring general-purpose agent-based models”) | Ascape development team |
| DIVA-GIS (“mapping and geographic data analysis”) | DIVA-GIS development team |
| EIO-LCA – Economic Input-Output Life Cycle Assessment | Green Design Institute, Carnegie Mellon University, PA |
| E-Net (“software for analyzing ego network data”) | Analytic Technologies |
| Envision (“A spatially explicit, distributed, multiagent-based framework for policy assessment and alternative futuring”) | Envision development team, Oregon State University |
| HLM – Hierarchical Linear and Nonlinear Modeling | Scientific Software International, Inc. |
| J-MADeM – Multi-modal Agent Decision Making (library integrated into Jason) | MADeM development team |
| Keyplayer (“Finding sets of key players in a network”) | Analytic Technologies |
| Krackplot (“Network visualization”) | Analytic Technologies |
| LISREL (“for structural equation modeling”) | Scientific Software International, Inc. |
| MASON – Multi-Agent Simulator Of Neighborhoods | GMU Evolutionary Computation Laboratory and GMU Center for Social Complexity |
| MATSim – Multi-Agent Transport Simulation | I.L.S.T.S., Technische Universität Berlin; I.T.P.S., Swiss Federal Institute of Technology, Zurich and Senozon |
| Mobidyc – MOdelling Based on Individuals for the DYnamics of Communities | Mobidyc development team |
| NetDraw (“program for visualizing social network data”) | Analytic Technologies |
| NetLogo | Uri Wilensky, Center for Connected Learning |
| Pajek | Batagelj et al., University of Ljubljana, Slovenia |
| Pandora (“HPC Agent-Based Modelling framework”) | Barcelona Supercomputing Center |
| Repast | Argonne National Laboratory |
| SOARS – Spot Oriented Agent Role Simulator | SOARS Project and Deguchi Lab, Tokyo Institute of Technology |
| SPADE – Smart Python multi-Agent Development Environment | SPADE development team |
| SPARK – Simple Platform for Agent-based Representation of Knowledge | SPARK development team |
| StarLogo/ OpenStarLogo | MIT |
| Sugarscape | Sugarscape development team |
| Swarm | Swarm Development Group |
| UCINET (“software package for the analysis of social network data”) | Analytic Technologies. |
| Worldmapper (“collection of world maps, where territories are re-sized on each map according to the subject of interest”) | Worldmapper Team |
Information Portals and Databases
Cumulative/Aggregate Exposures
Cumulative and aggregate exposure modeling for individuals and populations
Computational Analysis Tools
Information Portals and Databases
| Resource | Developer |
|---|---|
| AirBase (“European air quality database”) | European Environment Agency and European Topic Centre on Air Pollution and Climate Change and Mitigation (ETC/ACM) |
| ATUS – American Time Use Survey | U.S. Bureau of Labor Statistics |
| California Safe Cosmetics Program Product Database | California Safe Cosmetics Program, California Department of Public Health |
| CHAD – Consolidated Human Activity Database | USEPA |
| Child-Specific Exposure Factors Handbook | USEPA |
| Cosmeticsinfo.org | Personal Care Products Council |
| CPID – Consumer Product Information Database | CDC and DeLima Associates, Virginia, USA |
| EPA-Expo-Box – EPA’s EXPOsure toolBOX (“A Toolbox for Exposure Assessors”) | USEPA |
| ExpoCastDB – Exposure Forecaster Database | USEPA |
| EXPOLIS Database | Matti Jantunen, KTL Air Hygiene Laboratory, Finland |
| Exposure Factors Handbook | USEPA |
| Factual (“Global Products with Ingredients and Nutrition”) | Factual Inc. |
| GerES – German Environmental Survey | The Federal Environment Agency, Germany |
| HEDS – Human Exposure Database System | USEPA |
| iemHUB (“online community resource for those involved in the development, evaluation, and application of environmental models”) | iemHUB team |
| InterNano | National Nanomanufacturing Network |
| NHANES – National Health and Nutrition Examination Survey | CDC |
| NHEXAS – National Human Exposure Assessment Survey (project completed) | USEPA |
| RIOPA – Relationships of Indoor, Outdoor, and Personal Air | EOHSI and Health Effects Institute |
| SPARTAN – Surface PARTiculate mAtter Network | SPARTAN Network team |
| TEACH – Toxicity and Exposure Assessment for Children’s Health | USEPA |
| United Nations Statistical Yearbook | United Nations |
Biomarkers
Computational Analysis Tools
| Resource | Developer |
|---|---|
| Affymetrix Expression Console | Affymetrix |
| Affymetrix GeneChip Sequence Analysis Software | Affymetrix |
| Affymetrix Transcriptome Analysis Console | Affymetrix |
| BEs – Biomonitoring Equivalents | Summit Toxicology, LLP |
| BiQ Analyzer (“software tool for DNA methylation analysis”) | Max Planck Institute for Informatics, Germany |
| Bismark (tool to map bisulfite converted sequence reads and determine cytosine methylation states) | Babraham Bioinformatics |
| CMARRT (A tool for the analysis of ChIP-chip data from tiling arrays by incorporating the correlation structure) | Keles Research Group, University of Wisconsin |
| CNVFinder – Copy Number Variant Finder | Wellcome Trust Sanger Institute, UK |
| Compass | Bruker Daltonics |
| Compass OpenAccess | Bruker Daltonics |
| CSEM – Multi-read Allocation for ChIP-seq | Keles Research Group, University of Wisconsin |
| Cufflinks – Transcript assembly, differential expression and regulation for RNA-Seq samples | UC Berkeley, JHU, and Caltech |
| CummeRbund – To analyze Cufflinks RNA-Seq output | MIT and Harvard |
| DBChIP – program to detect differentially bound sharp binding sites across multiple conditions | Keles Research Group, University of Wisconsin |
| Disease/ Phenotype web-PAGE (“disease based gene set analysis of microarray gene expression”) | Gene Expression and Genomics Unit, NIA, NIH |
| EIGENSOFT (“combines functionality from our population genetics methods […] and our EIGENSTRAT stratification correction method”) | EIGENSOFT development team, Harvard School of Public Health |
| EpiGRAPH – for advanced (epi-) genome analysis and prediction | EpiGRAPH development team |
| flexImaging | Bruker Daltonics |
| FunDO (“Exploring Genes Using Functional Disease Ontology Annotations”) | Northwestern University Biomedical Informatics Center |
| GeneMANIA – “predict the function of […] genes and gene sets” | Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Canada |
| GeneSpring | Agilent Technologies |
| Genotyping Console | Affymetrix Inc |
| HDMFinder (“Methylation prediction software”) | Zhang Lab, Cold Spring Harbor Laboratory, NY |
| Ingenuity Variant Analysis | Qiagen |
| IPA – Ingenuity Pathway Analysis | Qiagen N.V. |
| jMOSAiCS – Joint Analysis of Multiple ChIP-seq Datasets | Keles Research Group, University of Wisconsin |
| MarkerView | AB Sciex |
| Mascot | Matrix Science |
| MENTOR – Modeling ENvironment for TOtal Risk studies | Computational Chemodynamics Laboratory |
| MetaboliteTools | Bruker Daltonics |
| Methylator (“An SVM Based Method for DNA Methylation Prediction”) | Methylator Development Team |
| MIDAS – Multi Instance Data Acquisition System | Science and Technology Facilities Council, UK |
| MOABS – MOdel based Analysis of Bisulfite Sequencing data | Deqiang Sun, Baylor College of Medicine |
| Monocle – toolkit for analyzing single-cell gene expression experiments | Cole Trapnell |
| MOSAiCS – MOdel-based one and two Sample Analysis and Inference for ChIP-Seq Data | Keles Research Group, University of Wisconsin |
| mzMINE | MZmine team (open-source) |
| NucDe – A non-homogeneous hidden-state model on first order differences for automatic detection of nucleosome positions from MNase-chip and MNase-seq data | Keles Research Group, University of Wisconsin |
| OmicsOffice for Microarrays | Integromics |
| PLINK (“Whole genome association analysis toolset”) | PLINK development team, CHGR – Massachusetts General Hospital, Boston, MA |
| PolyBayes (“automated analysis of single-nucleotide polymorphism (SNP) discovery in redundant DNA sequences”) | Washington University Genome Sequencing Center |
| Polyphred (single nucleotide substitution identification) | University of Washington (Brent Ewing, Phil Green, David Gordon et al.) |
| ProfileAnalysis | Bruker Daltonics |
| ProteinScape | Bruker Daltonics |
| ProteoIQ (“qualitative and quantitative suite for proteomics”) | Premier Biosoft |
| SCiLS (“Statistical analysis of MALDI imaging data”) | SCiLS GmbH and Bruker Daltonics |
| SICER (“clustering approach for identification of enriched domains from histone modification ChIP-Seq data”) | W. Peng lab, George Washington University |
| SMART-BS-Seq – Specific Methylation Analysis and Report Tool for BS-Seq data | Python Software Foundation |
| SNAP – Screening for Non-Acceptable Polymorphisms | Rost Lab, Columbia University, New York |
| SNAP – SNP Annotation and Proxy Search | SNAP Development Team |
| SNP-o-matic (analysis of Solexa reads and comparison with reference) | Sanger Institute |
| SNPTrack | USFDA |
| SUCcESS (Integration of quantitative information from ChIP-chip experiments into motif finding) | Keles Research Group, University of Wisconsin |
| TileHGMM (Mixture modeling for genome-wide localization of transcription factors) | Keles Research Group, University of Wisconsin |
| TopSpin (NMR data analysis and acquisition and processing of NMR spectra) | Bruker Corporation |
| Trinotate (“Transcriptome Functional Annotation and Analysis”) | Trinotate development team |
| Tute (“web application […] in the cloud and […] analyze and annotate entire human genomes”) | Tute Genomics |
| X-Tile | Yale University |
Information Portals and Databases
| Resource | Developer |
|---|---|
| AHEAD – Alliance for Human Epigenomics and Disease | AHEAD Task Force |
| ArrayExpress | EMBL-EBI |
| BioCarta | BioCarta LLC |
| BioGRID – Biological General Repository for Interaction Datasets | BioGRID Team |
| Biomarkers Database (last updated in August 2004) | USEPA |
| BOSS – Biomarkers of Oxidative Stress Study | NIEHS |
| CGAP – Cancer Genome Anatomy Project | NCI (National Cancer Institute), NIH |
| ChIPBase (“decoding transcription factor binding maps […] and transcriptional regulation […] from ChIP-Seq data”) | Qu lab at Sun Yat-sen University (J. Yang) |
| CNV Project Data – Copy Number Variation Project Data | Wellcome Trust Sanger Institute, UK |
| COSMIC – Catalogue Of Somatic Mutations In Cancer | Wellcome Trust Sanger Institute, UK |
| CureTogether (a blog where “patients […] share quantitative information on over 500 medical conditions”) | CureTogether team |
| dbGaP – Database of Genotypes and Phenotypes | National Center for Biotechnology Information, NLM, NIH |
| dbSNP | National Center for Biotechnology Information, NLM, NIH |
| EADB – Estrogenic Activity Database | USFDA |
| EDKB – Endocrine Disruptor Knowledge Base | USFDA |
| ENCODE – Encyclopedia Of DNA Elements | NHGRI, NIH |
| EPA-Expo-Box – EPA’s EXPOsure toolBOX (“A Toolbox for Exposure Assessors”) | USEPA |
| EPR – Environmental Polymorphisms Registry | NIEHS |
| EuPathDB – Eukaryotic Pathogen Database Resources | EuPathDB Project Team |
| ExpoCastDB – Exposure Forecaster Database | USEPA |
| GAC – Genetic Alterations in Cancer | NIEHS |
| GeMDBJ – Genome Medicine Database of Japan | SGMGP (The Study Groups of Millennium Genome Project for Alzheimer’s disease, Cancer, Diabetes Mellitus, Hypertension, Asthma and Pharmacogenetics) |
| GenAge Database | HAGR – Human Ageing Genomic Resources |
| GenBank | National Center for Biotechnology Information, NLM, NIH |
| Gene Expression Atlas | EMBL-EBI |
| Gene Finder | NCI (National Cancer Institute), NIH |
| GeneLoc | Weizmann Institute of Science |
| GeneTox | NLM |
| Genomatix Suite | Genomatix Software GmbH |
| GENSAT – Gene Expression Nervous System ATlas database | Rockefeller University |
| GVS – Genome Variation Server | University of Washington |
| GWAS Catalog – Genome-Wide Association Studies Catalog | NHGRI Division of Genomic Medicine, NIH |
| GWASdb | GWASdb team |
| HapMap | International HapMap Project |
| HEP – Human Epigenome Project | HEP Consortium |
| HEROIC – High-Throughput Epigenetic Regulatory Organization in Chromatin Project | HEROIC Project Consortium |
| HGMD – Human Gene Mutation Database (integrated with Ingenuity Variant Analysis) | BIOBASE |
| HIV Molecular Immunology Database | Los Alamos National Laboratory |
| HIV Sequence database | Los Alamos National Laboratory |
| HMPDACC Data Browser (Human Microbiome Project DACC Data Portal) | NIH Human Microbiome Project DACC |
| Human DNA Polymerase Gamma Mutation Database | NIEHS |
| IARC TP53 Database | IARC, WHO |
| IRD – Influenza Research Database | IRD Project Team |
| IUPHAR-DB – International Union of Basic and Clinical Pharmacology Database | IUPHAR-DB development team |
| JSNP – Japanese Single Nucleotide Polymorphisms | University of Tokyo and the Japan Science and Technology Agency (JST) |
| KEGG – Kyoto Encyclopedia of Genes and Genomes | Kanehisa Laboratories, Japan |
| KEGG DRUG | Kanehisa Laboratories, Japan |
| KUPKB – The Kidney and Urinary Pathway Knowledge Base | INSERM, France and University of Manchester, UK |
| MeInfoText | National Taiwan University |
| MethyCancer – Database for studying human DNA Methylation and Cancer | Chinese Academy of Sciences |
| microRNA.org | |
| Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer | University Hospital, Lund, Sweden |
| NCBI GEO – NCBI Gene Expression Omnibus database | National Center for Biotechnology Information, NLM, NIH |
| NHANES – National Health and Nutrition Examination Survey | CDC |
| NHATS – National Human Adipose Tissue Survey | USEPA |
| NHEXAS – National Human Exposure Assessment Survey (project completed) | USEPA |
| NIEHS SNPs Exome Variant Server | NIEHS and University of Washington |
| NIH Human Microbiome Project (HMP) Roadmap Project | National Center for Biotechnology Information, NLM, NIH |
| NIMH-RGR Data Explorer | NIMH Center for Collaborative Genomic Studies on Mental Disorders |
| NMPDR – National Microbial Pathogen Data Resource (no longer maintained; see PATRIC) | NMPDR Project Team |
| Nonhuman Primate HIV/SIV Vaccine Trials Database | Los Alamos National Laboratory |
| OMIM – Online Mendelian Inheritance in Man (“Online Catalog of Human Genes and Genetic Disorders”) | Johns Hopkins University and NCBI, NLM, NIH |
| Oncomine | Life Technologies Corporation |
| Pan Asian SNP Database | Pan-Asian SNP Consortium |
| Pathogen Portal | Pathogen Portal Project Team |
| PATRIC – Pathosystems Resource Integration Center | PATRIC Project Team |
| PD map – Parkinson’s disease map | LCSB and Hiroaki Kitano team at SBI, Tokyo |
| Progenetix (“genomic copy number aberrations in cancer”) | Baudis Laboratory, University of Zurich |
| PubMeth | BioBix, Laboratory for Bioinformatics and Computational Genomics, Ghent University, Belgium |
| Reactome | Reactome team |
| RefSeq – NCBI Reference Sequence Database | National Center for Biotechnology Information, NLM, NIH |
| SCAN (“SNP and CNV Annotation Database”) | The University of Chicago |
| SCan-MarK Explorer (“Sophic’s Cancer Biomarker Knowledge Environment”) | Sophic Alliance Inc. |
| SKY/M-FISH and CGH Database | National Center for Biotechnology Information, NLM, NIH and National Cancer Institute, NIH |
| SMD – Stanford Microarray Database (see PUMAdb) | Stanford University |
| SNP500Cancer | SAIC-Frederick, NCI-FCRDC, MD |
| SNPinfo Web Server | NIEHS |
| StemBase (gene expression data obtained from stem cells) | Canadian Stem Cell Network |
| TB Drug Target Database | TB Drug Target Database development team |
| TEAM – Total Exposure Assessment Methodology Study | USEPA |
Human Health Risks
Modeling human health risks
Computational Analysis Tools
Information Portals and Databases
| Resource | Developer |
|---|---|
| BCF database – Bio-concentration Factors Gold standard database | Cefic LRI and EURAS |
| Comprehensive Cancer Information | NCI (National Cancer Institute), NIH |
| CPDB – Carcinogenic Potency Database | CPDB development team |
| ECETOC Science Areas – European Centre for Ecotoxicology and Toxicology of Chemicals Science Areas | ECETOC |
| EPA-Expo-Box – EPA’s EXPOsure toolBOX (“A Toolbox for Exposure Assessors”) | USEPA |
| EuPathDB – Eukaryotic Pathogen Database Resources | EuPathDB Project Team |
| ExpoFacts – European Exposure Factors Sourcebook | European Commission, JRC, IHCP |
| Exposure Factors Handbook | USEPA |
| GAC – Genetic Alterations in Cancer | NIEHS |
| GeMDBJ – Genome Medicine Database of Japan | SGMGP (The Study Groups of Millennium Genome Project for Alzheimer’s disease, Cancer, Diabetes Mellitus, Hypertension, Asthma and Pharmacogenetics) |
| HEDS – Human Exposure Database System | USEPA |
| HERO – Health and Environmental Research Online database | USEPA |
| IARC Monographs- Classifications | IARC, WHO |
| ICRP – International Commission on Radiological Protection – Database of Dose Coefficients | ICRP |
| IRIS – Integrated Risk Information System | USEPA |
| NATA – National Air Toxics Assessments | USEPA |
| National Toxicology Program Technical Reports | NIEHS |
| NCTRlcdb – NCTR Liver Cancer Database | USFDA |
| PatientsLikeMe (network of patients sharing experiences on diseases) | PatientsLikeMe team |
| ToxGuides™ | ATSDR, CDC |
| Toxic Substances Portal | ATSDR, CDC |
| Unregulated Contaminant Monitoring data | USEPA |
| US Census Population Database | US Census Bureau |
| US Census Survey | US Census Bureau |
Ecological Risks
Modeling ecological risks from chemicals
Computational Analysis Tools
| Resource | Developer |
|---|---|
| 2MOD (“estimate the relative likelihoods of a model of immigration-drift equilibrium versus drift since a certain time”) | 2MOD team (M. Beaumont) |
| ACE – Acute-to-Chronic Estimation with Time-Concentration-Effect Models | USEPA |
| AGDISP – AGricultural DISPersal | USDA Forest Service |
| AgDRIFT | USEPA, USDA Forest Service and Spray Drift Task Force |
| AQUATOX (“simulation model for aquatic systems”) | USEPA and R. Park, Ecomodeling |
| AquiferWin32 | ESI Ltd. |
| ASTER – Assessment Tools for the Evaluation of Risk | USEPA |
| ATTILA – Analytical Tools Interface for Landscape Assessments | USEPA |
| BASS – Bioaccumulation and Aquatic System Simulator | USEPA |
| BIOPLUME III (“simulating the natural attenuation of organic contaminants in groundwater”) | US Air Force (Groundwater Services, Inc.) and the USEPA |
| BLM – Biotic Ligand Model | HydroQual |
| bsim-bccs (“Models the stochastic interactions of bacteria and particles in a fluid based environment”) | bsim-bccs development team |
| CalTOX | California DTSC |
| CASCADE | Alterra and Plant Research International |
| CE-QUAL-ICM | U.S. Army Corps of Engineers |
| CE-QUAL-W2 | U.S. Army Corps of Engineers and Portland State University |
| ChemStat (“statistical analysis of ground water monitoring data at RCRA facilities”) | Starpoint Software Inc. |
| COMBO – COral Mortality and Bleaching Output | COMBO Team |
| Cormas | Cormas development team, Cirad |
| DEBTox | University of Amsterdam |
| Defra Risk Assessment | Defra team and Department for Environment, Food & Rural Affairs |
| DFLOW | USEPA |
| DMR Pollutant Loading Tool – Discharge Monitoring Report Pollutant Loading Tool | USEPA |
| DROPLET | Alterra and Wageningen UR, The Netherlands |
| DUST (“model to calculate the dermal uptake of pesticides by birds and mammals”) | USEPA |
| ECOSAR – Ecological Structure Activity Relationships | Syracuse Research Corporation and USEPA |
| E-FAST – Exposure and Fate Assessment Screening Tool | USEPA |
| EMSOFT – Exposure Model for Soil-Organic Fate and Transport | RTP |
| EwE – Ecopath with Ecosim | International Center for Living Aquatic Resources Management, Philippines |
| EXAMS – Exposure Analysis Modeling System | USEPA |
| FGETS – Food and Gill Exchange of Toxic Substances | USEPA |
| FIRST – FQPA Index Reservoir Screening Tool | USEPA |
| FOCUS – FOrum for Co-ordination of pesticide fate models and their USe | FOCUS team, EU Commission |
| FRAMES-3MRA – Multimedia, Multi-pathway, Multi-receptor Exposure and Risk Assessment | USEPA |
| GARR – Gross Alpha Radium Regulation | USEPA |
| GBPCALC – Gross Beta Photon Calculator | USEPA |
| GENEEC2 – Generic Estimated Environmental Concentration | USEPA |
| Groundwater Vistas (“3D groundwater flow and contaminant transport modeling, calibration and optimization using the MODFLOW suite of codes”) | Groundwater Vistas development team |
| GUTS – General Unified Threshold model for Survival | GUTS team |
| HAIR – HArmonized environmental Indicators for pesticide Risk | Alterra and Wageningen UR, The Netherlands |
| HexSim (previously PATCH) | USEPA |
| IONEX – Ion Exchange | USEPA |
| IsoConc | USEPA |
| IsoError | USEPA |
| IsoSource | USEPA |
| iSTREEM | American Cleaning Institute |
| KABAM – Kow (based) Aquatic BioAccumulation Model | USEPA |
| MASTEP – Metapopulation model for Assessing Spatial and Temporal Effects of Pesticides | Alterra and Wageningen UR, The Netherlands |
| Mercury Maps | USEPA |
| NWPCAM – Nation Water Pollution Control Assessment Model | USEPA |
| P2P – Pollution Prevention Progress (see TRACI) | USEPA |
| PATCH – Program to Assist in Tracking Critical Habitat (see HexSim) | USEPA |
| PEARL – Pesticide Emission Assessment at Regional and Local scales, GeoPEARL | Alterra, PBL and RIVM |
| PERPEST – Predicts the Ecological Risks of PESTicides in freshwater ecosystems | Alterra and Wageningen UR, The Netherlands |
| PFAM – Pesticides in Flooded Application Model | USEPA |
| PRIMET – Pesticides RIsks in the tropics to Man, Environment and Trade | Alterra and Wageningen UR, The Netherlands |
| PRZM/EXAMS Shell | USEPA |
| PRZM-GW | USEPA |
| QUAL2E (Enhanced Stream Water Quality model) | Tufts University and USEPA |
| QUAL2K – River and Stream Water Quality Model | USEPA |
| RAMAS GIS | Applied Biomathematics |
| ReachScan | USEPA |
| R-UNSAT | USGS |
| SERAFM – Spreadsheet-based Ecological Risk Assessment for the Fate of Mercury | USEPA |
| SIP – Screening Imbibition Program (“model to estimate chemical exposure from drinking water alone in birds and mammals”) | USEPA |
| SPEAR – SPEcies At Risk Calculator/ TU – Toxic-Unit Calculator | UFZ Leipzig |
| STIR – Screening Tool for Inhalation Risk | USEPA |
| SWASH – Surface WAter Scenarios Help | Alterra and Wageningen UR, The Netherlands |
| TerrPLANT | USEPA |
| T-HERPS – Terrestrial Herpetofaunal Exposure Residue Program Simulation (“to estimate dietary exposure and risk to terrestrial-phase amphibians and reptiles from pesticide use”) | USEPA |
| Tier 1 Rice Model (“estimate surface water exposure from the use of pesticides in rice paddies”) | USEPA |
| TOXSWA – TOXic substances in Surface WAters | TOXSWA team |
| TRACI – Tool for the Reduction and Assessment of Chemical and other Environmental Impacts (previously, P2P) | USEPA |
| T-REX – Terrestrial Residue Exposure (“model to calculate the residues on avian and mammalian food items”) | USEPA |
| ubertool (“Cloud-based environmental models for evaluating pesticide risks to ecosystems”) | USEPA |
| USEtox – UNEP-SETAC (Life Cycle Initiative) Tox | USEtox development team |
| WASP – Water Quality Analysis Simulation Program | USEPA |
| Watershed Plan Builder | USEPA |
| Web-ICE – Web-based Interspecies Correlation Estimation | USEPA |
| WHATIF – Watershed Health Assessment Tools Investigating Fisheries | Canaan Valley Institute and USEPA |
Information Portals and Databases